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NEXOVELBioscience
RedShift Bio

Aurora TX

See your biomolecule in any buffer.

Infrared-based structure, binding and stability characterization of proteins, peptides, antibodies, RNAs, LNPs, ADCs, IDPs and more — directly in native buffer.

Aurora TX instrument

Overview

What it does

The AuroraTX platform combines a high-performance quantum cascade laser, a precision-engineered microfluidic flow cell, and automated spectral analytics to deliver high-resolution structural insight. By eliminating buffer exchange, dilution, and the need for spectroscopy expertise, Microfluidic Modulation Spectroscopy (MMS) overcomes the core limitations of traditional techniques and makes label-free structural analysis easy — even in the most complex formulations.

Because structure is tightly linked to function, even subtle structural changes can reduce biological activity, trigger aggregation, alter ligand binding, and impact safety, stability and manufacturability. Aurora TX surfaces those shifts with the sensitivity and reproducibility modern biotherapeutics demand.

Key Features

Why teams choose it

Analyze in native buffer

No buffer exchange, no dilution — measure your sample as formulated.

30× higher sensitivity than FTIR, 5× CD

Detect subtle structural changes invisible to legacy techniques.

Built-in thermal ramping

Smarter formulation and stability decisions in a single run.

Real-time background subtraction

Ultra-clean, quantitative spectra with automated reference correction.

>98% microfluidic precision

High-precision microfluidics deliver reproducible, comparable results.

Fully automated workflow

Reduced training time with integrated software and automated data analysis.

Applications

Built for these workflows

  • Proteins & antibodies

    Higher-order structure and aggregation profiling.

  • Peptides & IDPs

    Sensitive secondary-structure characterization.

  • RNAs & oligonucleotides

    Conformational analysis of therapeutic nucleic acids.

  • LNPs & ADCs

    Structural integrity in complex formulations.

  • Formulation & stability

    Thermal-ramp profiling and forced-degradation studies.

  • Comparability studies

    Quantitative structural comparison across batches.

Talk to an expert

Ready to see Aurora TX in action?

Our team in Navi Mumbai supports demos, application discussions and procurement across India.