HaLCon
Chromatography without complexity.
Accurate, actionable protein titer in minutes, not days — purpose-built for bioreactor sampling, IgG quantitation and mAb production.
Overview
What it does
HaLCon delivers immediate, actionable protein-titer data for bioreactor sampling and process control — keeping workflows on track and reducing costly hold times in continuous manufacturing. At Lonza, HaLCon replaced slow HPLC measurements with rapid, accurate titer data, helping teams spot issues earlier, make faster decisions and reduce delays. With HPLC-level accuracy (R² > 0.99) and a 5-minute time-to-result, HaLCon brings chromatography-grade titer into the hands of every bioprocess scientist — without the method development.
Key Features
Why teams choose it
5-minute titer
Decisions in minutes, not days.
Crude samples, no prep
Run crude samples without dilution or extensive preparation.
Low sample volume
Inject just 100 μL.
HPLC-level accuracy
R² > 0.99 against reference HPLC titer.
Autosampler-ready
Scale throughput with seamless autosampler integration.
Compact, GMP-ready
Footprint built for development and GMP labs.
Applications
Built for these workflows
Bioreactor sampling
Real-time titer for process control and continuous manufacturing.
IgG quantitation
Rapid antibody titer across discovery and development.
mAb production
Spot issues earlier in upstream processes.
Clone selection
Higher-throughput screening of producer cell lines.
Configuration
Packaging & integration
HaLCon analyzer is compatible with the Nest Autosampler for multi-sample automation — holds up to 2 × 96-well plates or 2 × 48 (2 mL vial) racks, with cooling and non-cooling options, and integrates with the Sartorius Ambr® 15/250 bioreactor.
Resources
Brochures & downloads
Talk to an expert
Ready to see HaLCon in action?
Our team in Navi Mumbai supports demos, application discussions and procurement across India.
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